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plus renal, liver and dialysis adjustments Morphine serves as the prototypical opiate with regard to analgesic and side effects for other opiate derivatives 6 It is absorbed in the upper intestine and the mucosa of the rectum, while it is eliminated renally and via enterohepatic circulation, primarily as morphine-3-glucuronide (M3G) 3, 4 Morphine is available as branded and generic products in multiple dosage forms and can be go drugbank com salts DBSALT001753— webmd com drugs 2 drug-327-604 morphine-oral detailsgo drugbank com drugs DB00295Morphine-6-glucuronide is responsible for approximately 85% of the response observed by morphine administration 4 Morphine and its metabolites act as agonists of the mu and kappa opioid receptors 1 The mu-opioid receptor is integral to morphine’s effects on the ventral tegmental area of the brain — drugs com cdi morphine-immediate-release-tablets-and-capsules htmlCommon Brand (S): MS Contin Generic Name (S): morphine Uses This medication is used to help relieve severe ongoing pain (such as due to cancer) Morphine belongs to a class of drugs known as Common Brand (S): MS Contin Generic Name (S): morphine Uses This medication is used to help relieve severe ongoing pain (such as due to cancer) Morphine belongs to a class of drugs known as Tilidine A synthetic opioid indicated in the treatment of severe pain Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated Sufentanil An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain go drugbank com categories DBCAT000480Morphine hydrochloride Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805 1 It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse 2 Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine Morphine is 35% protein bound, the metabolite morphine -3-glucuronide is 10% protein bound, and morphine -6-glucuronide is 15% protein bound 4 Metabolism Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate 6 MORPHINE treats severe pain It is prescribed when other pain medications have not worked or cannot be tolerated It works by blocking pain signals in the brain It belongs to a group of medications called opioids Get morphine for as low as $15 81, which is 77% off the average retail price of $69 84 for the most common version, by using a Find patient medical information for morphine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings Find patient medical information for morphine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings Find patient medical information for morphine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings Benzodiazepines may be used to treat many health problems like anxiety, trouble sleeping, or seizures If you have questions, talk with your doctor Many drugs interact with this medicine (morphine immediate-release tablets and capsules) and can raise the chance of side effects like deadly breathing problems — drugs com dosage morphine htmlaccp1 onlinelibrary wiley com doi full 10 1002 jcph 1873— webmd com drugs 2 drug-327-819 morphine-oral morphine-oral detailslink springer com article 10 1007 s15006-021-0284-yMorphine may cause other serious side effects Call your doctor at once if you have: slow heart rate, weak pulse, fainting, slow breathing (breathing may stop); 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